RecruitingNot ApplicableNCT06408220

Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer

OUR Stomach Health Project: A Pilot Study to Evaluate the Feasibility of Stomach Cancer Risk Assessment for Early Detection and Secondary Prevention


Sponsor

City of Hope Medical Center

Enrollment

240 participants

Start Date

Jun 27, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial evaluates the usefulness of various risk assessment tests, including Helicobacter pylori (H. pylori) breath testing, questionnaires, and endoscopies for identifying participants at high risk for stomach cancer. H. pylori is a bacteria that causes stomach inflammation and ulcers in the stomach. People with H. pylori infections may be more likely to develop cancer in the stomach. H. pylori breath testing can help identify the presence of H. pylori infection in a participant and help identify if the participant may be at a higher risk of developing stomach cancer. An endoscopy uses a thin, flexible lighted tube that is inserted inside the esophagus, stomach, and first part of the small intestine. This allows the doctor to see and look for abnormal areas that may need to be biopsied. Risk assessment including H. pylori evaluation, questionnaires, and endoscopies may help identify participants at high risk for stomach cancer and may be a useful screening tool for earlier stomach cancer diagnosis.


Eligibility

Min Age: 40 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study aims to identify people in racial minority groups (Asian, Hispanic, or Black American) who may be at high risk for stomach cancer or pre-cancerous stomach conditions, using a risk scoring tool and an upper endoscopy (a camera exam of the stomach). **You may be eligible if...** - You are between 40 and 80 years old - You identify as Asian, Hispanic, or Black American - You are willing to provide a blood sample and have an upper endoscopy **You may NOT be eligible if...** - You identify as Non-Hispanic White - You have a personal history of stomach cancer - You have already had a known pre-cancerous stomach lesion - You had an upper endoscopy within the past 2 years - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBiopsy

Undergo tissue biopsy

PROCEDUREBiospecimen Collection

Undergo blood sample collection

PROCEDUREBreath Test

Undergo H. pylori breath test

PROCEDUREEsophagogastroduodenoscopy

Undergo EGD

OTHERQuestionnaire Administration

Complete questionnaires


Locations(1)

City of Hope Medical Center

Duarte, California, United States

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NCT06408220


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