RecruitingNCT04314401

National Cancer Institute "Cancer Moonshot Biobank"

Cancer Moonshot Biobank Research Protocol

Sponsor

National Cancer Institute (NCI)

Enrollment

1,600 participants

Start Date

Nov 11, 2020

Study Type

OBSERVATIONAL

Conditions

Ovarian Carcinoma Esophageal Carcinoma Gastric Carcinoma Malignant Solid Neoplasm Primary Peritoneal Carcinoma Melanoma Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IV Breast Cancer AJCC v8 Clinical Stage IV Gastric Cancer AJCC v8 Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 Stage III Lung Cancer AJCC v8 Stage IV Lung Cancer AJCC v8 Triple-Negative Breast Carcinoma Metastatic Prostate Carcinoma Stage III Ovarian Cancer AJCC v8 Stage IV Ovarian Cancer AJCC v8 Hormone Receptor-Positive Breast Carcinoma Stage IV Colorectal Cancer AJCC v8 Acute Myeloid Leukemia Invasive Breast Carcinoma Fallopian Tube Carcinoma Multiple Myeloma Lung Non-Small Cell Carcinoma Clinical Stage IV Esophageal Adenocarcinoma AJCC v8 Lung Small Cell Carcinoma Ovarian High Grade Serous Adenocarcinoma Stage III Fallopian Tube Cancer AJCC v8 Stage IV Fallopian Tube Cancer AJCC v8 Stage IVB Prostate Cancer AJCC v8

Summary

This trial collects multiple tissue and blood samples, along with medical information, from cancer patients. The "Cancer Moonshot Biobank" is a longitudinal study. This means it collects and stores samples and information over time, throughout the course of a patient's cancer treatment. By looking at samples and information collected from the same people over time, researchers hope to better understand how cancer changes over time and over the course of medical treatments.

Eligibility

Min Age: 13 Years

Plain Language Summary

Simplified for easier understanding

This is the National Cancer Institute's 'Cancer Moonshot Biobank' — a large study that collects blood and tissue samples from patients with advanced cancers over time to study how cancers change in response to treatment. The goal is to speed up cancer research and drug development. **You may be eligible if...** - You have advanced cancer of one of these types: colorectal (stage IV), lung (stage III/IV), prostate (metastatic), gastric/esophageal/GEJ (stage IV), ovarian (stage III/IV), breast (stage III/IV), melanoma (stage III/IV), acute myeloid leukemia, or multiple myeloma - You are about to start a new line of treatment, just started treatment, are currently responding to treatment, or are progressing on current treatment **You may NOT be eligible if...** - You do not have one of the cancer types listed above at the required stage - You are unable to provide tissue or blood samples as required - You cannot provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBiospecimen Collection

Undergo collection of blood, tissue, bone marrow, and cerebral spinal fluid samples

PROCEDUREComputed Tomography

Undergo CT

PROCEDUREMagnetic Resonance Imaging

Undergo MRI

OTHERMedical Chart Review

Medical charts are reviewed and data is collected

PROCEDUREParacentesis

Undergo paracentesis

PROCEDUREPositron Emission Tomography

Undergo PET/CT

Locations(152)

Gulf Health Hospitals Inc/Infirmary Cancer Care - Malbis

Daphne, Alabama, United States

Thomas Hospital

Fairhope, Alabama, United States

Mobile Infirmary Medical Center

Mobile, Alabama, United States

Gulf Health Hospitals Inc/Infirmary Cancer Care - Saraland

Saraland, Alabama, United States

Kingman Regional Medical Center

Kingman, Arizona, United States

Mercy Hospital Fort Smith

Fort Smith, Arkansas, United States

PCR Oncology

Arroyo Grande, California, United States

AIS Cancer Center at San Joaquin Community Hospital

Bakersfield, California, United States

Veterans Affairs Loma Linda Healthcare System

Loma Linda, California, United States

Salinas Valley Memorial

Salinas, California, United States

Intermountain Health Platte Valley Hospital

Brighton, Colorado, United States

Saint Joseph Hospital - Cancer Centers of Colorado

Denver, Colorado, United States

Lutheran Hospital - Cancer Centers of Colorado

Golden, Colorado, United States

Saint Mary's Hospital and Regional Medical Center

Grand Junction, Colorado, United States

Good Samaritan Hospital - Cancer Centers of Colorado

Lafayette, Colorado, United States

Hartford Hospital

Hartford, Connecticut, United States

Bayhealth Hospital Kent Campus

Dover, Delaware, United States

Bayhealth Hospital Sussex Campus

Milford, Delaware, United States

Boca Raton Regional Hospital

Boca Raton, Florida, United States

Broward Health North

Deerfield Beach, Florida, United States

Broward Health Medical Center

Fort Lauderdale, Florida, United States

Tampa General Hospital

Tampa, Florida, United States

Northside Hospital

Atlanta, Georgia, United States

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Savannah, Georgia, United States

Illinois CancerCare-Bloomington

Bloomington, Illinois, United States

John H Stroger Jr Hospital of Cook County

Chicago, Illinois, United States

Swedish Covenant Hospital

Chicago, Illinois, United States

Carle at The Riverfront

Danville, Illinois, United States

Cancer Care Specialists of Illinois - Decatur

Decatur, Illinois, United States

Decatur Memorial Hospital

Decatur, Illinois, United States

NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, United States

Illinois CancerCare-Galesburg

Galesburg, Illinois, United States

NorthShore University HealthSystem-Glenbrook Hospital

Glenview, Illinois, United States

NorthShore University HealthSystem-Highland Park Hospital

Highland Park, Illinois, United States

Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, United States

SSM Health Good Samaritan

Mount Vernon, Illinois, United States

Illinois CancerCare-Pekin

Pekin, Illinois, United States

Illinois CancerCare-Peoria

Peoria, Illinois, United States

Carle Cancer Center

Urbana, Illinois, United States

Illinois CancerCare - Washington

Washington, Illinois, United States

McFarland Clinic - Ames

Ames, Iowa, United States

University of Iowa Healthcare Cancer Services Quad Cities

Bettendorf, Iowa, United States

Physicians' Clinic of Iowa PC

Cedar Rapids, Iowa, United States

Oncology Associates at Mercy Medical Center

Cedar Rapids, Iowa, United States

Blank Children's Hospital

Des Moines, Iowa, United States

Iowa Methodist Medical Center

Des Moines, Iowa, United States

UI Health Care Mission Cancer and Blood - Des Moines Clinic

Des Moines, Iowa, United States

University of Iowa/Holden Comprehensive Cancer Center

Iowa City, Iowa, United States

Our Lady of the Lake Physician Group

Baton Rouge, Louisiana, United States

University Medical Center New Orleans

New Orleans, Louisiana, United States

Children's Hospital New Orleans

New Orleans, Louisiana, United States

LSU Health Sciences Center at Shreveport

Shreveport, Louisiana, United States

Harold Alfond Center for Cancer Care

Augusta, Maine, United States

MaineHealth Waldo Hospital

Belfast, Maine, United States

MaineHealth Maine Medical Center - Biddeford

Biddeford, Maine, United States

MaineHealth Cancer Care and IV Therapy - Brunswick

Brunswick, Maine, United States

Mid Coast Hospital

Brunswick, Maine, United States

MaineHealth LincolnHealth Hospital

Damariscotta, Maine, United States

MaineHealth Franklin Hospital

Farmington, Maine, United States

Saint Mary's Regional Medical Center

Lewiston, Maine, United States

MaineHealth Stephens Hospital

Norway, Maine, United States

Maine Medical Partners Surgical Care

Portland, Maine, United States

MaineHealth Maine Medical Center - Portland

Portland, Maine, United States

MMP Surgical Care Casco Bay

Portland, Maine, United States

Penobscot Bay Medical Center

Rockport, Maine, United States

MaineHealth Cancer Care and IV Therapy - Sanford

Sanford, Maine, United States

Maine Children's Cancer Program

Scarborough, Maine, United States

Maine Medical Partners Neurology

Scarborough, Maine, United States

MaineHealth Maine Medical Center- Scarborough

Scarborough, Maine, United States

MaineHealth Cancer Care and IV Therapy - South Portland

South Portland, Maine, United States

MaineHealth Urology - South Portland

South Portland, Maine, United States

Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, Michigan, United States

Trinity Health Medical Center - Brighton

Brighton, Michigan, United States

Trinity Health Medical Center - Canton

Canton, Michigan, United States

Chelsea Hospital

Chelsea, Michigan, United States

Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, United States

Dickinson County Healthcare System

Iron Mountain, Michigan, United States

Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, United States

Trinity Health Saint Joseph Mercy Oakland Hospital

Pontiac, Michigan, United States

Mercy Oncology and Hematology - Clayton-Clarkson

Ballwin, Missouri, United States

Freeman Health System

Joplin, Missouri, United States

Mercy Hospital Joplin

Joplin, Missouri, United States

Mercy Clinic-Rolla-Cancer and Hematology

Rolla, Missouri, United States

Phelps Health Delbert Day Cancer Institute

Rolla, Missouri, United States

Heartland Regional Medical Center

Saint Joseph, Missouri, United States

Mercy Hospital Springfield

Springfield, Missouri, United States

CoxHealth South Hospital

Springfield, Missouri, United States

Mercy Infusion Center - Chippewa

St Louis, Missouri, United States

Mercy Hospital South

St Louis, Missouri, United States

Missouri Baptist Medical Center

St Louis, Missouri, United States

Mercy Hospital Saint Louis

St Louis, Missouri, United States

Mercy Hospital Washington

Washington, Missouri, United States

Saint Vincent Frontier Cancer Center

Billings, Montana, United States

Saint James Community Hospital and Cancer Treatment Center

Butte, Montana, United States

Nebraska Cancer Specialists/Oncology Hematology West PC

Grand Island, Nebraska, United States

Carson Tahoe Regional Medical Center

Carson City, Nevada, United States

OptumCare Cancer Care at Seven Hills

Henderson, Nevada, United States

OptumCare Cancer Care at Charleston