RecruitingPhase 4NCT06408688

Safety and Modulation of Adaptive Immunity by Iscador® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors

Safety and Modulation of Adaptive Immunity by Iscador® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors - a Randomized Trial


Sponsor

University Hospital, Basel, Switzerland

Enrollment

100 participants

Start Date

Jun 24, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The main objective of this study is to test if adding the mistletoe extract Iscador® Qu to regular cancer treatment with immune checkpoint inhibitors affects: * The immune system's ability to fight cancer * Safety of the treatment * How well the treatment performs against cancer * How the patient feels during treatment Researchers will compare patients treated with immune checkpoint inhibitors plus Iscador® Qu with patients treated with imune checkpoint inhibitors only.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Immune Checkpoint Inhibitors and a drug called Immune checkpoint inhibitors plus Iscador® Qu. for people with advanced solid tumor. The study is currently recruiting participants at 4 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGImmune checkpoint inhibitors plus Iscador® Qu.

Standard cancer treatment plus subcutaneous injection of mistletoe fermented extract (Iscador® Qu) as per the summary of product characteristics.

DRUGImmune Checkpoint Inhibitors

Standard cancer treatment.


Locations(4)

Kantosspital Baden AG

Baden, Switzerland

Universitätsspital Basel

Basel, Switzerland

Kantonsspital Baselland

Liestal, Switzerland

Tumor- und Brustzentrum Ostschweiz

Sankt Gallen, Switzerland

View Full Details on ClinicalTrials.gov

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NCT06408688


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