Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer
A Pilot Study of Sequential ("First Strike, Second Strike") Therapies, Modeled on Evolutionary Dynamics of Anthropocene Extinctions, for Hormone Positive Metastatic Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute
15 participants
Aug 14, 2024
INTERVENTIONAL
Conditions
Summary
The purpose of the study is to test a treatment strategy with currently approved drugs to see if it is practical to administer the available drugs in a new way that researchers hope could be more effective in treating metastatic breast cancer.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
75 mg/m2 once every 21 days for 4 cycles
600 mg/m2 once every 21 days for 4 cycles
5.4 mg/kg once every 21 days for 5 cycles
10 mg/kg on days 1 and 8 cycled every 21 days for 5 cycles
1000 mg/m2 orally twice daily for 14 days cycled every 21 days for 5 cycles
500 mg intramuscular (IM) on days 1, 15 and 28 of the first cycle followed by every 28 days for a total of 4 cycles
600 mg orally daily 21 days on, 7 days off
150 mg by mouth twice daily
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06409390