RecruitingPhase 4NCT06411925

The Efficacy and Safety of Atock Dry Syrup With Acute Bronchitis Patients

A Multi-center, Randomized, Double-blinded, Active-controlled, Non-inferiority, Phase 4 Trial to Evaluate the Efficacy and Safety of Atock Dry Syrup Sama With Acute Bronchitis Patients


Sponsor

SamA Pharmaceutical Co., Ltd

Enrollment

296 participants

Start Date

Nov 10, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Clinical Study to Evaluate the Efficacy and Safety of Atock Dry Syrup with Acute bronchial Patients


Eligibility

Min Age: 6 MonthsMax Age: 11 Years

Inclusion Criteria5

  • Children aged ≥6 months to \<12 years old
  • Total Bronchitis Severity Scale excluding sputum(BSSEs) ≥4
  • Wheezing score ≥2
  • Subjects who present symptoms of Acute Bronchitis within 48 hours from screening visit
  • Subject with negative results in HbsAg or HCV Ab test within 6 months from screening visit

Exclusion Criteria5

  • Subjects with chronic respiratory diseases (e.g., asthma, COPD) or severe respiratory diseases (e.g., pneumonia, cystic fibrosis, influenza, active tuberculosis)
  • Subjects under treatment with corticosteroids, antibiotics medications
  • Subjects with severe hepatic and renal impairment
  • Subjects with a history of drug abuse
  • Subject with positive results in HIV Ab test

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Interventions

DRUGAtock Dry Syrup with placebo patch

Atock Dry syrup (TID) with placebo patch (QD)

DRUGTulobuterol patch with placebo dry syrup

Tulobuterol patch (QD) with placebo dry syrup (TID)


Locations(1)

Soonchunhyang University Seoul Hospital

Seoul, South Korea

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NCT06411925


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