RecruitingPhase 1Phase 2NCT06412510

Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT

Prehabilitation for Elderly Patients With Advanced Epithelial Ovarian, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer Undergoing Neoadjuvant Chemotherapy


Sponsor

Case Comprehensive Cancer Center

Enrollment

22 participants

Start Date

Sep 5, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to see whether participants who are assigned to a multimodal prehabilitation intervention during chemotherapy are able to adhere with exercise and nutrition program to prepare for their cancer surgery.


Eligibility

Min Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study tests a "prehabilitation" program for older adults (65+) who are about to start chemotherapy for certain advanced cancers. Prehabilitation means getting physically and mentally prepared for treatment before it begins — like training before a race — to help people handle treatment better and recover faster. **You may be eligible if...** - You are 65 years or older - You have advanced ovarian, fallopian tube, or peritoneal cancer, pancreatic cancer, esophageal cancer, or muscle-invasive bladder cancer - You are about to start neoadjuvant chemotherapy (chemo given before surgery) **You may NOT be eligible if...** - Your expected survival is less than 3 months - You use a wheelchair or are physically immobile - You have severe heart or lung disease (NYHA class III–IV) - You have a bowel obstruction requiring surgery - You cannot provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERPrehabilitation

Exercise Intervention: SmartGyms, band or smartphone used to scan into the TechnoGym MyWellness kiosk, which controls the TechnoGym Excite Live and Biostrength equipment. The exercise session will consist of a program that adheres to the FITT (Frequency, Intensity, Timing, and Type) exercise prescription in accordance with ACSM 2018 ACSM Roundtable recommendations for Physical Function for combined Aerobic and Resistance training. Nutrition Intervention: 30 gm protein supplement Supportive care/Mind-body intervention: Yoga, mindfulness practices, art therapy, and music therapy


Locations(1)

Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center

Cleveland, Ohio, United States

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NCT06412510


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