RecruitingEarly Phase 1NCT06412952
68Ga-NOTA-RM26 PET/CT in Glioma Patients
Sponsor
Peking Union Medical College Hospital
Enrollment
30 participants
Start Date
Oct 1, 2022
Study Type
INTERVENTIONAL
Conditions
Summary
The aim of this study was to investigate the value of 68Ga-NOTA-RM26, an antagonist targeting gastrin-releasing peptide receptor (GRPR) PET tracer, in the diagnosis of high WHO grade glioma and prediction the grade of glioma using positron-emission tomography/computed tomography (PET/CT).
Eligibility
Min Age: 18 YearsMax Age: 80 Years
Inclusion Criteria2
- suspected or confirmed untreated glioma patients
- signed written consent.
Exclusion Criteria5
- pregnancy
- breastfeeding
- known allergy against Pentixafor
- any medical condition that in the opinion of the investigator,may
- significantly interfere with study compliance
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Interventions
DRUG68Ga-RM26
Intravenous injection of one dosage of 74-185 MBq(2-5 mCi) 68Ga-RM26. Tracer doses of 68Ga- RM26 will be used to image lesions of glioma by PET/CT.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06412952
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