RecruitingPhase 1NCT06414889

Protocol Title: Safety and Feasibility of Autologous CD34+ Hematopoietic Stem Cells Mobilization and Apheresis in Participants With RUNX1 Familial Platelet Disorder


Sponsor

M.D. Anderson Cancer Center

Enrollment

4 participants

Start Date

May 20, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate the safety and feasibility of collecting hematopoietic stem cells (HSC) in participants with RUNX1-FPD.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Apheresis, a drug called G-CSF (filgrastim or biosimilar), and others for people with runx1 familial platelet disorder. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGG-CSF (filgrastim or biosimilar)

Given by IV or SC

PROCEDUREApheresis

Given by procedure

DRUGPlerixafor

Given by IV


Locations(1)

MD Anderson Cancer Center

Houston, Texas, United States

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NCT06414889