RecruitingPhase 2NCT06416228

Beetroot Juice NO Cold Study

Beetroot Juice Supplement for Boosting Mucosal Immunity - The NO Cold Study


Sponsor

Southern Methodist University

Enrollment

150 participants

Start Date

Apr 2, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Currently, there is a lack of evidence-based prevention strategies for respiratory infection and management of these conditions can be costly to the public. Airway nitric oxide provides a first line of defense against pathogens, and beetroot juice, a source of dietary nitrate, has been shown to elevate nitric oxide. The main objective of this project is to demonstrate that one week of supplementation with beetroot juice elevates airway nitric oxide during stressful periods in young adults and thereby can protect against respiratory viral infections.


Eligibility

Min Age: 18 YearsMax Age: 30 Years

Inclusion Criteria3

  • Individuals will be included:
  • SMU or Baylor University students
  • Ages of 18-30 years old.

Exclusion Criteria12

  • Active smokers
  • Smoking cannabis or vape
  • Students with clinically significant asthma
  • COPD and emphysema
  • Allergic rhinitis
  • High levels of exhaled nitric oxide (FENO ≥40ppb)
  • Developing kidney stone
  • Clinically significant heart disease
  • Cerebrovascular disease
  • Thyroid dysfunction
  • Out-of-control diabetes
  • Significant current problems with schizophrenia, psychosis, mood disorders, suicidality, and drug or alcohol dependence or abuse

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Interventions

DIETARY_SUPPLEMENTBeetroot juice

Participants will take on dose in the morning and one in the afternoon, for 7 days during their final academic examinations


Locations(2)

Southern Methodist University

Dallas, Texas, United States

Baylor University

Waco, Texas, United States

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NCT06416228


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