RecruitingNCT06418412

A Pan-Asian Clinical Database of EGFR Exon 20 Insertion Mutated NSCLC

A Pan-Asian Clinical Database of EGFR Exon 20 Insertion Mutated Non-small Cell Lung Cancer (NSCLC)


Sponsor

National Cancer Centre, Singapore

Enrollment

600 participants

Start Date

Mar 15, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

There are limited in depth studies on the epidemiology and clinical management of EGFR exon 20 insertion mutated NSCLC in Asia. In addition, there is preliminary data suggesting the exact location of the insertion and variant may influence the response and efficacy to novel EGFR targeted therapies. This study aims to fill this knowledge gap, by comprehensively characterising the epidemiology and clinical outcomes of Asian advanced EGFR exon 20 insertion mutated NSCLC patients.


Eligibility

Min Age: 21 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This study is creating a large pan-Asian database of clinical information on patients with a specific type of lung cancer called EGFR Exon 20 insertion-mutated NSCLC (non-small cell lung cancer). This rare mutation is harder to treat with standard EGFR drugs, and this registry aims to improve understanding of real-world treatment patterns and outcomes across Asia. **You may be eligible if...** - You have been diagnosed with advanced NSCLC confirmed by biopsy - Your tumor has been tested and found to have an EGFR Exon 20 insertion mutation - You were diagnosed between January 1, 2013 and December 31, 2024 - You are an adult (age requirements follow local regulations) **You may NOT be eligible if...** - Your tumor does not have an EGFR Exon 20 insertion mutation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.


Locations(3)

National Cancer Centre, Singapore

Singapore, Singapore

Seoul National University Hospital

Seoul, South Korea

National Taiwan University Hospital

Taipei, Taiwan

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06418412