[68Ga]Ga-Sa-DABI-4 PET Imaging of Stimulator of Interferon Gene Expression in Cancer Patients
First Affiliated Hospital of Chongqing Medical University
30 participants
May 30, 2024
INTERVENTIONAL
Conditions
Summary
Stimulator of interferon gene (STING) protein plays a vital role in the immune surveillance of tumor microenvironment. Monitoring STING expression in tumors benefits the relevant STING therapy. This study will investigate the safety, biodistribution and potential usefulness of a novel 68Ga-labeled agonist (\[68Ga\]Ga-Sa-DABI-4) for noninvasive positron emission tomography (PET) imaging of STING expression in the tumor microenvironment.
Eligibility
Plain Language Summary
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Interventions
Each subject receives a single intravenous injection of \[68Ga\]Ga-Sa-DABI-4.
Locations(1)
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NCT06419361