RecruitingNCT06419413

A Translational Study to Describe Clinical Characteristics, Biomarkers and to Identify Phenotypes and Endotypes Associated With Differential Outcomes in Chinese Population

A Transnational Study to Describe Asthma Patient Clinical Characteristics, Treatment Patterns, Biomarkers and to Identify Phenotypes and Endotypes Associated With Differential Outcomes That May Support Future Development of Personalized Treatment Strategies in Chinese Population


Sponsor

AstraZeneca

Enrollment

355 participants

Start Date

Jan 8, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

A Translational Study to Describe Asthma Patient Clinical Characteristics, Treatment Patterns, Biomarkers and to Identify Phenotypes and Endotypes associated with Differential Outcomes that may Support Future Development of Personalised Treatment Strategies in Chinese Population


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria4

  • Age 18 to 75 years of age
  • acceptable FEV1 (according to ATS and ERS)
  • compliance with study procedures All Asthma Cohorts
  • physician diagnosed Asthma greater or equal to 3 months prior to screening visit

Exclusion Criteria7

  • history of alcohol or drug abuse within the past year
  • pregnant at time of an assessment
  • has an altered mental status at the time of informed consent
  • receipt marketed or investigational biologic(s) within 3 months or 5 half-lives prior to visit 1, whichever is longer
  • history or current upper or lower respiratory infection or symptoms within 2 weeks of baseline assessments
  • terminal diseases and/or organ failure or participants otherwise considered not appropriate for the study participation
  • Receipt LTRAs or 5-lipoxygenase (5-LO) inhibitors (eg zileuton and montelukast) within 1 month or 5 half-lives prior to baseline, whichever is longer.

Locations(21)

Research Site

Chengdu, Sichuan, China

Research Site

Beijing, China

Research Site

Changsha, China

Research Site

Dongguan, China

Research Site

Foshan, China

Research Site

Guangzhou, China

Research Site

Hainan, China

Research Site

Hohhot, China

Research Site

Huizhou, China

Research Site

Kunming, China

Research Site

Nanjing, China

Research Site

Nanning, China

Research Site

Shanghai, China

Research Site

Shenyang, China

Research Site

Taiyuan, China

Research Site

Wenzhou, China

Research Site

Wuhan, China

Research Site

Xi'an, China

Research Site

Xuzhou, China

Research Site

Zhanjiang, China

Research Site

Zhaoqing, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06419413


Related Trials