RecruitingNot ApplicableNCT06421077

Transcutaneous Auricular Vagus Nerve Stimulation Prevents Postoperative Delirium in Elderly Patients

Transcutaneous Auricular Vagus Nerve Stimulation （taVNS）Prevents Postoperative Delirium in Elderly Patients: a Randomized Controlled Study

Sponsor

Beijing Tiantan Hospital

Enrollment

1,776 participants

Start Date

Jun 20, 2024

Study Type

INTERVENTIONAL

Conditions

Vagus Nerve Stimulation

Summary

According to the 3D-CAM scale, evaluate the incidence of Postoperative Delirium within 5 days after surgery in elderly patients receiving taVNS.The results are expected to provide evidence of the safety and efficacy of perioperative prophylactic use of taVNS in the clinical application of improving postoperative brain health in elderly patients, as well as theoretical and practical basis for subsequent studies or clinical applications.

Eligibility

Min Age: 65 Years

Inclusion Criteria4

Age≥65 years
Expected operation time≥ 2 hours
Postoperative hospital stay≥ 4 days
Sign the informed consent form

Exclusion Criteria5

Neurosurgery or cardiac surgery
Emergency surgery within 6 hours of admission
End-stage disease with an expected survival of \< 3 months
Preoperative severe cognitive dysfunction affected perioperative cognitive function assessment
Severe sinus bradycardia, AVB of degree II and above, pacemaker placement

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