RecruitingNot ApplicableNCT06421090

Transauricular Vagal Nerve Stimulation Improves Postoperative Delirium in Elderly Patients

Safety and Feasibility of Transauricular Vagus Nerve Stimulation in Improving Postoperative Delirium in Elderly Patients: a Randomized Controlled Study

Sponsor

Beijing Tiantan Hospital

Enrollment

150 participants

Start Date

May 21, 2024

Study Type

INTERVENTIONAL

Conditions

Vagus Nerve Stimulation

Summary

To investigate the efficacy and safety of perioperative Transauricular vagal nerve stimulation in improving Postoperative Delirium in elderly patients undergoing elective surgery Lay the groundwork for a Phase III study.

Eligibility

Min Age: 65 Years

Inclusion Criteria4

Age≥65 years
Expected operation time≥ 2 hours
Postoperative hospital stay≥ 4 days
Sign the informed consent form

Exclusion Criteria5

Neurosurgery or cardiac surgery
Emergency surgery within 6 hours of admission
End-stage disease with an expected survival of \< 3 months
Preoperative severe cognitive dysfunction affected perioperative cognitive function assessment
Severe sinus bradycardia, AVB of degree II and above, pacemaker placement

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