Nephroprotective Effect of Nicorandil in Type 2 Diabetes Mellitus

This study is testing whether nicorandil — a drug normally used to treat chest pain (angina) by opening blood vessels — can protect the kidneys in people with early-stage chronic kidney disease (CKD) who also have Type 2 diabetes. Researchers want to see if the drug slows kidney decline. **You may be eligible if...** - You have been newly diagnosed with Type 2 diabetes that is well-controlled with diet alone (HbA1c below 7) - You are between 18 and 60 years old - You have Stage 1 or Stage 2 chronic kidney disease according to standard guidelines - Your blood pressure is controlled **You may NOT be eligible if...** - You are pregnant or breastfeeding - You are allergic to nicorandil - Your kidney disease is caused by uncontrolled blood pressure, kidney cancer, a connective tissue disorder (like lupus), or a disease like amyloidosis or rheumatic fever - You are taking blood pressure medications such as ACE inhibitors or ARBs, or other specific antihypertensive drugs - You are taking medications that are toxic to the kidneys (such as aminoglycosides, NSAIDs, or contrast dyes) Talk to your doctor to see if this trial is right for you.