EMI Therapy for Depression in Hong Kong

This study is testing a smartphone app-based therapy called EMI (Ecological Momentary Intervention) — which delivers real-time, personalized mental health support throughout the day — for people with moderate to severe depression in Hong Kong. The goal is to see whether app-assisted therapy improves depression outcomes compared to standard care. **You may be eligible if...** - You are between 16 and 65 years old - You are an ethnic Chinese person who speaks Cantonese - You have been diagnosed with a major depressive episode (MDE) according to DSM-5 criteria - Your depression severity is moderate to severe (score of 14 or higher on the Hamilton Depression Rating Scale) - You own a smartphone with internet access (iOS or Android) **You may NOT be eligible if...** - You cannot read Chinese or are unable to provide informed consent - You have another major psychiatric diagnosis alongside depression (especially schizoaffective disorder) - You have an unstable medical condition or current substance abuse - You have significant psychotic symptoms (delusions or hallucinations) - You are at serious risk of self-harm or suicide that cannot be safely managed as an outpatient - You are currently receiving another weekly psychotherapy - You are unable to use a smartphone app Talk to your doctor to see if this trial is right for you.