Hyaluronic Acid Delivery: CO2 Laser Versus Thulium Laser Treatment
In Vivo Visualisation of Hyaluronic Acid After CO2 Laser Compared to Thulium Laser Treatment
Universitätsklinikum Hamburg-Eppendorf
30 participants
Feb 20, 2024
INTERVENTIONAL
Conditions
Summary
* Weakly crossed-linked hyaluronic acid (HA) can be delivered through multiple injections into the dermal and subnormal layer to improve skin quality. However, this treatment comes with multiple bumps for several days. * Alternatively, HA can be delivered after CO2 laser or thulium laser pretreatment. As microscopic analysis after this treatment is limited, the object of the present study is to investigate the morphological cellular changes after CO2 laser and thulium laser delivered HA into human skin.
Eligibility
Inclusion Criteria1
- \- healthy male and female patients
Exclusion Criteria2
- pregnancy, breast feeding
- open wounds at the area to be treated
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Interventions
Probands will be treated with a CO2 laser. Afterwards a HA gel will be applied. To measure microscopic cellular changes, a multiphoton tomography will be used.
Probands will be treated with a thulium laser. Afterwards a HA gel will be applied. To measure microscopic cellular changes, a multiphoton tomography will be used.
Locations(1)
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NCT06431282