RecruitingPhase 4NCT06433310

Understanding the Efficacy of Dietary Supplement on Fungal Mycobiota in Healthy Volunteers: A Pilot Study

Sponsor

Weill Medical College of Cornell University

Enrollment

20 participants

Start Date

Oct 17, 2024

Study Type

INTERVENTIONAL

Conditions

Gut health Gut Microbiome Dietary Supplement L-Phenylalanine Phenylpropionic Acid

Summary

The purpose of this study is to explore how the dietary supplement L-Phenylalanine affects the production of the metabolite phenylpropionic acid (PPA) and changes fungal populations of the gut microbiome.

Eligibility

Min Age: 18 Years

Inclusion Criteria1

Male or female adults over the age of 18 years

Exclusion Criteria6

History of a diagnosis of any gastrointestinal condition, such as inflammatory bowel syndrome or disease
Antibiotic usage within the past two weeks
Antifungal usage within the past month
Allergy to L-Phenylalanine or individuals with phenylketonuria (PKU)
Adults taking medications known to interact with L-phenylalanine supplements, such as Monoamine Oxidase Inhibitors (MOAI), L-DOPA, and some antipsychotic drugs (complete and extensive drug list will be provided to interested participants during screening)
Pregnant or nursing women

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