RecruitingNCT06435195

Clinical Characteristics and Analysis of Pituitary Complex and Rare Diseases


Sponsor

Peking Union Medical College Hospital

Enrollment

3,000 participants

Start Date

Jan 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to systematically describe the clinical characteristics and outcomes of patients with pituitary complex and rare diseases at Peking Union Medical College Hospital. The main questions it aims to answer are: * What are the influencing factors and rates of remission? * What are the comorbidities associated with these diseases? * What are the perioperative events, radiological findings, and pathological features? Researchers will compare different patient groups to see if there are significant differences in these outcomes. Participants will: * Undergo detailed clinical evaluations. * Provide medical history and data for analysis. * Participate in follow-up assessments to monitor disease progression and treatment outcomes.


Eligibility

Inclusion Criteria2

  • Diagnosed with rare sellar diseases including but not limited to pituitary adenomas (such as Thyrotropin-secreting pituitary adenomas, GH-secreting adenomas), craniopharyngiomas, Rathke's cleft cysts, sellar region germ cell tumors, cavernous sinus syndrome, and other diseases
  • Detailed medical history, including clinical symptoms, treatment plans and follow-up outcomes

Exclusion Criteria3

  • Incomplete medical records, especially missing key imaging diagnostic results
  • Patients with coexisting primary central nervous system diseases unrelated to sellar region diseases (such as severe traumatic brain injury)
  • Patients whose sellar region pathological diagnosis was changed or overturned during the follow-up period

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Interventions

PROCEDURESurgical Removal

Resection of pituitary pathologies.

PROCEDUREBiopsy

Taking a small tissue or liquid sample from the pituitary pathologies and the affected area for examination and diagnosis


Locations(1)

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

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NCT06435195