RecruitingNot ApplicableNCT06438094

The Influence of Non-Carious Cervical Lesions on Root Coverage

The Influence of Non-Carious Cervical Lesions on Root Coverage by Means of Coronally Advanced Flap and a Connective Tissue Graft: A Prospective Cohort Study

Sponsor

Gonzalo Blasi

Enrollment

56 participants

Start Date

May 26, 2024

Study Type

INTERVENTIONAL

Conditions

Gingival Recession

Summary

The goal of this prospective cohort study is to evaluate the effect of non-carious cervical lesions (NCCLs) on the outcome of root coverage therapy. The main question it aims to answer is: In gingival recessions associated with NCCLs, characterized by an undetectable cemento-enamel junction (CEJ), reconstruction of the CEJ with a cervical composite restoration, prior to root coverage surgery by means of a coronally advanced flap combined with a connective tissue graft (CAF+CTG), provides similar clinical and patient-reported outcomes, as compared to the treatment of gingival recessions associated with NCCLs, characterized by a visible CEJ, with root coverage surgery only, by means of a CAF+CTG. In NCCLs where the CEJ is undetectable (B-type defect), the CEJ will be reconstructed before surgery with a cervical composite restoration mimicking the anatomic features of the contralateral, homologous tooth. CAF+CTG treatment will be performed in all cases. Participants will be assessed at 6 weeks, 3 months, and 6 months to evaluate clinical, volumetric, and patient-centred outcomes.

Eligibility

Min Age: 18 Years

Inclusion Criteria5

Systemically healthy individuals older than 18 years old;
Healthy periodontal status according to the AAP/EFP definition;
Full-mouth plaque (FMPS) and bleeding scores (FMBS) ≤ 20%;
At least one facial RT1 GR in single-rooted teeth with a minimum depth of 2 mm, associated with a NCCL;
No history of periodontal surgery at the experimental site(s).

Exclusion Criteria6

Pregnancy or lactation;
Self-reported smoking ≥10 cigarettes/day;
Metabolic diseases that negatively affect soft tissue healing (i.e., diabetes mellitus);
Any medication that may interfere with wound healing;
Prosthetic crown at experimental teeth;
Ongoing orthodontic therapy.

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Interventions

PROCEDURERoot coverage surgery by means of a coronally advanced flap combined with a connective tissue graft

A root coverage surgery will be performed using Zucchelli et al.'s coronally advanced flap combined with a connective tissue graft from the palate.

PROCEDUREReconstruction of the CEJ with a composite restoration followed by root coverage surgery by means of a coronally advanced flap combined with a connective tissue graft

Reconstruction of the CEJ with a composite restoration will be performed in B+ and B- defects prior to root coverage surgery. A root coverage surgery will be performed using Zucchelli et al.'s coronally advanced flap combined with a connective tissue graft from the palate.