RecruitingNot ApplicableNCT06441136

Characterizing the Impact of Presbyphonia on Social Interaction


Sponsor

Matthew R. Hoffman

Enrollment

25 participants

Start Date

Jan 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to determine if presbyphonia, or voice disorder caused by age-related change in the larynx, is associated with change in social interaction. This proposal investigates the impact of voice impairment in older adults on social interaction, loneliness, social disconnectedness, and depression. A series of questionnaires, voice assessments, and interviews will be performed to improve our understanding of how voice disorders affect older adults and how treatment of voice impairment with voice therapy may improve quality of life.


Eligibility

Min Age: 65 Years

Inclusion Criteria3

  • Diagnosis of presbyphonia with findings of presbylaryngis on videostroboscopy, with findings of bilateral true vocal fold atrophy and normal vocal fold motion bilaterally
  • Able to complete all questionnaires and voice assessment tasks
  • Normal to mild hearing loss in aided condition (with hearing aids)

Exclusion Criteria4

  • Liquid dysphagia or pneumonia in the last year
  • Vocal fold lesion/scar/motion impairment
  • Neurologic disorder affecting the voice
  • Montreal cognitive assessment score <26 or <25 if 12 or fewer years of formal education

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Interventions

OTHERPhoRTE Program

Speech therapy program guided by a speech language pathologist. This program includes in person or virtual visits and at home exercises.

OTHERUniversity of California Los Angeles (UCLA) Loneliness Scale

A questionnaire measuring levels of loneliness.

OTHERSocial Disconnectedness Scale

A questionnaire that asks about social network size and the frequency of social activities attended.

OTHERPatient Health Questionnaire 9

A questionnaire measuring levels of depression.

OTHERAging Voice Index

A questionnaire of patient-reported voice outcome measures designed to capture the quality of life impact of dysphonia in older adults.

OTHERThe Edmonton Frail Scale

A questionnaire that measures frailty levels.

OTHERVocal Effort Scale

A picture based questionnaire scale that asks the subject to rate their perceived effort when using their voice.

OTHERMontreal Cognitive Assessment

A screening tool used to test for cognitive impairment.

OTHERVoice Handicap Index-10

A questionnaire used to measure quality of life impact of dysphonia.

OTHERVoice Problem Impact Scales

A 4 question survey that captures impact of voice on four domains - work/daily activities, social life, home, and overall quality of life.

OTHERCough Severity Index

A 10 question survey asking to rate severity of cough.

PROCEDURELaryngoscopy

Nose is anesthetized and a flexible endoscope is passed to visualize the larynx at rest and during sustained vowel production (/i/) for 3-5 seconds. This will be used to measure bowing index and normalized glottal gap of the vocal folds.

OTHERAcoustic, perceptual, and aerodynamic assessments

Participants will complete voice recording tasks including sustained vowel production, six standard sentences, and 20 seconds of natural conversational speech. This will be used to measure CAPE-V rating, Cepstral peak prominence, fundamental frequency, signal-to-noise ratio, voice type components, mean flow rate, subglottal pressure, and vocal efficiency.


Locations(1)

University of Iowa Hospitals & Clinics

Iowa City, Iowa, United States

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NCT06441136