RecruitingPhase 2NCT06441812

A Study to Evaluate the Long-term Safety, Pharmacodynamics and Efficacy of SHR-1703 in Eosinophilic Asthma Patients

A Multicenter, Single-group Phase II Clinical Study to Evaluate the Long-term Safety, Pharmacodynamics and Efficacy of Multiple Subcutaneous Injections of SHR-1703 in Eosinophilic Asthma Patients


Sponsor

Guangdong Hengrui Pharmaceutical Co., Ltd

Enrollment

200 participants

Start Date

Jul 19, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evaluation the long-term Safety, Pharmacodynamics and Efficacy of SHR-1703 in Eosinophilic Asthma Patients


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This long-term study evaluates the safety and ongoing effectiveness of SHR-1703 — a new biologic injection — for people with eosinophilic asthma, a type of asthma driven by high levels of eosinophils (a type of immune cell that causes airway inflammation and makes breathing difficult). **You may be eligible if...** - You are 18 years old or older and weigh at least 40 kg - You have been diagnosed with asthma for at least 1 year - Your asthma is currently treated with medium or high-dose inhaled corticosteroids plus another controller medication - Your eosinophil levels and asthma severity meet the study's thresholds **You may NOT be eligible if...** - You have another serious lung disease (such as COPD) - You have had a severe asthma attack requiring hospitalization recently - You are on other biologic medications for asthma - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSHR-1703 Injection

SHR-1703 Injection


Locations(1)

West China Hospital of Sichuan University

Chengdu, Sichuan, China

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NCT06441812