RecruitingNot ApplicableNCT06444347

Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair

The Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair in Robotic Anti-Reflux Surgery: A Multi-Institutional Randomized Trial


Sponsor

Weill Medical College of Cornell University

Enrollment

200 participants

Start Date

Jun 10, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this study is to find out if using a certain kind of mesh can reduce the chances of hiatal hernias coming back after anti-reflux surgery. Participants undergoing antireflux surgery will be assigned to one of two groups, a group that has surgery with mesh, or a group that has surgery without mesh.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Documented diagnosis of gastroesophageal reflux disease
  • Adults aged 18 years or older
  • English speaking
  • Subject is planned to undergo surgery for reflux disease

Exclusion Criteria4

  • Physician deems the subject is unable to complete the study due to documented dementia.
  • Subject is undergoing emergent surgery.
  • Pregnancy
  • Patient has known allergy to tetracycline hydrochloride or kanamycin sulfate

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Interventions

DEVICEBiosynthetic Mesh

The biosynthetic mesh group will undergo hiatal hernia repair with Phasix Mesh (Becton Dickinson, Franklin Lakes, NJ) reinforcement, secured with permanent suture.

PROCEDUREHiatal Hernia Repair

The non-mesh group will undergo hiatal hernia repair with permanent suture only.


Locations(6)

University of Southern California Keck School of Medicine

Los Angeles, California, United States

Louisiana State University School of Medicine

New Orleans, Louisiana, United States

Washington University School of Medicine

St Louis, Missouri, United States

NYU Langone Health

New York, New York, United States

Weill Cornell Medicine

New York, New York, United States

Lenox Hill Hospital

New York, New York, United States

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NCT06444347


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