Washed Microbiota Transplantation for Malnutrition
The Second Hospital of Nanjing Medical University
100 participants
Dec 17, 2023
OBSERVATIONAL
Conditions
Summary
Malnutrition is a pathological condition in which dietary intake fails to meet the body's energetic or nutritional needs. It may be caused by macronutrient or micronutrient deficiencies, high energy expenditure, impaired nutrient absorption or assimilation. Malnutrition can affect all stages of life. In adults, malnutrition is strongly associated with poor clinical outcomes such as increased morbidity, increased mortality and prolonged hospitalization. In children, malnutrition can lead to growth retardation, cognitive impairment and immune dysfunction.
Eligibility
Inclusion Criteria3
- Age ≥18 years old;
- Meet any of the following two conditions: ①weight loss (>5% weight loss in the past 6 months or >10% weight loss in more than 6 months); ②low BMI (<70 years old and BMI<18.5kg/m2 or ≥70 years old and BMI<22kg/m2);
- Underwent washed microbiota transplantation.
Exclusion Criteria3
- Expected survival time <3 months;
- Women who are pregnant or breastfeeding;
- Other patients deemed not suitable for enrollment by the investigator.
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Interventions
The prepared microbiota suspension was infused into the patients' gut.
Locations(1)
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NCT06447220