Fragility Re-fractures Prediction Score
RIFRA - Re-fracture Risk Prediction in Patients With Fragility Fracture: Score Development and Validation
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
800 participants
May 28, 2024
OBSERVATIONAL
Conditions
Summary
Fragility fractures increase among elderly patients worldwide, representing a global burden in terms of disability and care expenditure. Osteoporosis is asymptomatic up to the moment in which a first fracture occurs, reason why it is often underdiagnosed. Even after that, further fractures do occurr, as osteoporosis is often untreated. Several programs have been introduced worldwide to prevent secondary fractures among the population at risk (e.g., International Osteoporosis Foundation's Capture the Fracture), and several risk factors are being investigated to generate a predictive score. However, accurate validation is needed to make these scores reliable. In this retrospective observational study, we aim to validate a predictive score trained on a population of elderly patients with a cohort of patients who underwent hip fracture surgery in a high-volume orthopedic center in the Region of Lombardy.
Eligibility
Inclusion Criteria1
- People who underwent total or partial hip replacement (ICD 9 CM 81.51, 81.52) in five years (2013-2017) at the hospital for a compound fracture of the hip (ICD 9 CM 820, 820.01-820.09).
Exclusion Criteria2
- People undergoing the same intervention for other reasons (e.g. pathological fracture, ICD 9 CM 733.14).
- ICD 9 CM stands for International Classification of Disease, 9th Revision, Clinical Modification.
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Interventions
Surgical treatment of the hip after osteoporosis fracture. The focus of the study is the prediction of further fractures (and therefore further surgical procedures) after the first one.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06448325