RecruitingPhase 1NCT06450106

Study of STM-416p Administered to Patients Undergoing Radical Prostatectomy

A Phase 1 Dose Escalation Study of STM-416p Administered Intraoperatively to Patients Undergoing Radical Prostatectomy


Sponsor

SURGE Therapeutics

Enrollment

18 participants

Start Date

May 8, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

A Study of STM-416p Administered Intraoperatively to Patients Undergoing Radical Prostatectomy


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial tests STM-416p, an experimental drug, in men with prostate cancer who are scheduled to have their prostate surgically removed (radical prostatectomy). The drug is given before surgery to see how it affects the tumor. **You may be eligible if...** - You are a male aged 18 or older - You have histologically confirmed prostate cancer with Gleason grade group 2–5 - You are scheduled for radical prostatectomy within 28 days - You have adequate organ and bone marrow function **You may NOT be eligible if...** - You have another invasive cancer other than prostate cancer - Your overall health (ECOG status) is too poor (greater than 2) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSTM-416p

STM-416p monotherapy


Locations(4)

Arizona Urology Specialists

Tucson, Arizona, United States

University of Florida

Gainesville, Florida, United States

Australian Prostate Center

Melbourne N., Victoria, Australia

Epworth HealthCare

Melbourne N., Victoria, Australia

View Full Details on ClinicalTrials.gov

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NCT06450106


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