RecruitingNot ApplicableNCT06451874

Personalized Exercise Treatments for Older Veterans With Motoric Cognitive Risk Syndrome

Motoric Cognitive Risk Syndrome: Refining Treatment Strategies and Testing Feasibility to Personalize Treatment for Older Veterans


Sponsor

VA Office of Research and Development

Enrollment

54 participants

Start Date

Jul 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study will begin to evaluate personalized preventative dementia treatments for Veterans at risk for developing dementia. The investigators will target Veterans with Motoric Cognitive Risk syndrome (MCR), which is characterized by slow gait speed and cognitive concerns (e.g., problems with memory or concentrations).


Eligibility

Min Age: 65 Years

Inclusion Criteria4

  • Age 65
  • Receiving VA primary care
  • Community-dwelling
  • Motoric Cognitive Risky Syndrome i. Slow gait speed ii. Subjective cognitive concerns/complaints

Exclusion Criteria7

  • Non-English speaking
  • Presence of a terminal disease
  • Major medical problem
  • Myocardial infarction or major surgery in the previous 3 months
  • point walking pattern
  • Dementia diagnostic
  • Mobility disability

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Interventions

BEHAVIORALFunctional Power Training (FPT)

Participants will receive twice weekly FPT, a progressive functional-based exercises that target optimizing leg force production and leg velocity.

BEHAVIORALMusic-Based Digital Therapy (MBDT)

Participants will receive twice weekly MBDT, a technology-driven gait training that is grounded in evidence-based rehabilitation treatment, rhythmic auditory stimulation.

BEHAVIORALFPT + MBDT

For non-responders who were randomized to augment treatment, they will receive combined FPT and MBDT treatment.


Locations(1)

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

Boston, Massachusetts, United States

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NCT06451874


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