RecruitingPhase 2NCT06452719

Letrozole and Misoprostol for Early Pregnancy Loss Management

Letrozole and Misoprostol for Early Pregnancy Loss Management: A Prospective Pilot Cohort Study

Sponsor

University of Pennsylvania

Enrollment

30 participants

Start Date

Aug 22, 2024

Study Type

INTERVENTIONAL

Conditions

early pregnancy loss Miscarriage Miscarriage in First Trimester

Summary

A pilot cohort study to preliminarily investigate the efficacy of pretreatment with letrozole 10 mg daily for three consecutive days followed by treatment with misoprostol 800 mcg vaginally for medical management of early pregnancy loss in a US population. Patients will be followed to assess efficacy of this treatment regimen, as well as additional interventions needed, side effects, adverse events, and patient acceptability.

Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Letrozole and a drug called Misoprostol for people with miscarriage, miscarriage in first trimester, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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