RecruitingNCT06459115

Adherence to Medication in Patients With Acute Decompensated Heart Failure

Adherence to Medication in Patients With Acute Decompensated Heart Failure: a Cross-sectional Study at the Emergency Department (ADHF-ED= Adherence to Medication in Patients With Acute Decompensated Heart Failure at the Emergency Department)

Sponsor

Universität des Saarlandes

Enrollment

100 participants

Start Date

Feb 1, 2023

Study Type

OBSERVATIONAL

Conditions

Acute Decompensated Heart Failure

Summary

Every day, patients present to emergency department due to acute heart failure. There are many causes for decompensation. One possible cause is a lack of adherence to heart failure medication (prognosis-improving medications and diuretics). The aim of this study is to directly measure adherence in patients with acute heart failure (gold standard of adherence measurement using liquid chromatography coupled to high-resolution mass spectrometry= LC-HRMS/MS) at the emergency department. Questionnaires are used to investigate possible factors influencing adherence.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at medication adherence (whether patients take their prescribed heart failure medications consistently) in people hospitalized for a worsening of their heart failure. The goal is to identify factors that affect whether patients take their medications as directed. **You may be eligible if...** - You are 18 or older - You have a known diagnosis of chronic heart failure, regardless of how well your heart pumps - You require intravenous diuretics (water pills given through an IV) to manage fluid buildup - You have been on stable heart failure medications for at least 2 weeks - You have signs of fluid overload (swollen legs, fluid in the lungs, distended neck veins, or abdominal fluid) - Your blood natriuretic peptide level is elevated (a marker of heart stress) **You may NOT be eligible if...** - You do not have chronic heart failure - You do not show signs of volume overload - You have not been on stable heart medications Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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