RecruitingNCT06462625

Clinical and Radiological Results of Long Term Tibial and Femoral Osteotomy in Knee Ostheoarthritis With Concomitant Lower Limb Malalignement

Long-term Clinical and Radiographic Outcomes of Different Knee Osteotomy Techniques for the Treatment of Compartmental Knee Osteoarthritis With Lower Limb Malalignment.


Sponsor

Istituto Ortopedico Rizzoli

Enrollment

150 participants

Start Date

Jan 12, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The present study aims to evaluate the long-term and medium-term outcomes of different knee osteotomy techniques in the treatment of knee osteoarthritis in patients with lower limb malalignment. This evaluation is necessary in the current context of research on the treatment and prevention of knee osteoarthritis through treatments that do not involve or allow for the postponement of prosthetic replacement. Among the biological treatments performed in orthopedic clinical practice, osteotomy is one of the most promising. However, further long-term evaluations are needed to more clearly determine the indications and potential of this type of intervention, considering the various surgical procedures described for performing it.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria4

  • Patients undergoing corrective knee osteotomy and any associated procedures such as meniscal repair/resection/replacement, ligament reconstruction, chondral treatment, or regenerative infiltrative treatment;
  • Patients aged between 18 and 70 years at the time of surgical intervention;
  • Patients with isolated compartmental osteoarthritis;
  • Patients with a varus or valgus knee alignment defect of at least 3° compared to mechanical neutrality.

Exclusion Criteria4

  • Patients with advanced multicompartimental osteoarthritis;
  • Patients who are no longer reachable;
  • Women of childbearing age who cannot exclude pregnancy;
  • Patients unable to give informed consent or patients unwilling to sign the informed consent form.

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Interventions

OTHERHigh tibial osteotomy

Correction of lower limb malalignement with tibial bone wedge insertion/removal


Locations(1)

IRCCS Istituto Ortopedico Rizzoli

Bologna, Italy

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NCT06462625


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