RecruitingNot ApplicableNCT06464432

Complex-Posttraumatic Stress Disorder in Urban Egypt: Pilot Testing of a Culturally-adapted Evidence-Based Treatment Manual and Development of a Culture-specific Diagnostic


Sponsor

University of Lausanne

Enrollment

20 participants

Start Date

Aug 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Background: The CPTSD diagnosis presented in the ICD-11 is supposed to provide core and culturally invariant symptoms, which is supported by recent research. Yet, evidence also shows the necessity of integrating culture-specific symptoms in intervention and diagnostic tools to enhance the validity and efficacy of such diagnoses and therapeutic interventions. Along with cultural aspects, there are relevant structural aspects e.g., economic, and social inequalities, which impact mental health. These aspects remain understudied in low middle income countries like Egypt, where there are considerable rates of violence. Aims: The project aims to i) culturally adapt and pilot test the therapeutic manual ESTAIR/MPE in urban Egypt, and ii) to pilot test a cultural and structural module for the diagnostic assessment of CPTSD among the same target population. The objective is to assess the feasibility, acceptability, and initial impact on clinical outcomes of both the manual and diagnostic modules. Methods: In earlier phases, the project gathered qualitative data from key informants on the cultural and structural dimensions of CPTSD in urban Egypt. Using the collected data, investigators culturally adapted this intervention and developed a diagnostic cultural module. Subsequently, the investigators will pilot-test it in four groups of five participants each, 20 participants in total. The project intends to collect both quantitative and qualitative measures to explore determined outcomes and analyze them accordingly.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is adapting and testing a psychological treatment for Complex PTSD — a condition caused by repeated or prolonged trauma — in Egyptian adults living in urban areas. It also aims to develop a culturally appropriate way to diagnose the condition. **You may be eligible if...** - You are Egyptian and 18 or older - You can read/write or give oral consent - You have experienced severe or prolonged trauma and screen positive for Complex PTSD - You live in a major city **You may NOT be eligible if...** - You are at immediate risk of suicide or experiencing psychotic symptoms - You have already completed a course of psychotherapy (more than 5–10 sessions) - You have severe alcohol or drug problems Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALEnhanced Skills Training in Affective and Interpersonal Regulation

Enhanced Skills Training in Affective and Interpersonal Regulation combined with Modified Prolonged Exposure (ESTAIR); Psychotherapeutic manual for the treatment of Complex Post-Traumatic Stress Disorder (CPTSD) consisting of 4 therapeutic modules: 1. Emotion Regulation, 2, Self-concept, 3. Relationship Patterns, 4. Prolonged Exposure.


Locations(1)

The American University in Cairo

Cairo, Egypt

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NCT06464432


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