RecruitingNot ApplicableNCT06464536
Evaluation of the Efficacy of Compression With Tight Surgical Gloves in Patients With Taxane-based Therapy
Tight Surgical Gloves to Prevent Chemotherapy-induced Peripheral Neuropathy: A Randomized Controlled Trial to Evaluate the Efficacy of Compression Therapy in Patients With Taxane-based Chemotherapy for Breast and Urogenital Cancer
Sponsor
St.Gallen University of Applied Sciences
Enrollment
114 participants
Start Date
Feb 3, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
In this study, the effect of compression therapy of the hands with tight surgical gloves to reduce peripheral neuropathy in adult patients during the application of taxanes will be evaluated.
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- Mamma or Urogenital carcinoma
- first treatment with Taxanes (nab-Paclitaxel, Paclitaxel, Docetaxel)
- signed informed consent
- sufficient proficiency in German or English
Exclusion Criteria4
- other therapy that could have caused peripheral neuropathy within the last 24 months (Taxane, Platin, Vincaalkaloids, etc.)
- History of neuropathy such as Raynaud's phenomenon, fibromyalgia and diabetic polyneuropathy
- Use of polyneuropathy medications including duloxetine; gabapentin/pregabalin; topical amitriptyline, ketamine, baclofen; oral cannabinoids; tricyclic antidepressants; and ganglioside monosialic acid
- such impaired cognition that prevents participation in the study according to the assessment of the caregivers
Interventions
OTHERCompression
conventional surgical gloves that are commonly used in hospitals will be used for compression therapy of both hands
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06464536