RecruitingNot ApplicableNCT06465498

Investigating aCute heArt failuRe Decongestion Guided by Lung UltraSonography

Investigating aCute heArt failuRe Decongestion Guided by Lung UltraSonography (IcarUS) : a Randomized Controlled Trial

Sponsor

Antonio Leidi

Enrollment

222 participants

Start Date

Oct 22, 2024

Study Type

INTERVENTIONAL

Conditions

Acute Heart Failure

Summary

The goal of this clinical trial is to investigate whether a lung ultrasonography (LUS)-guided decongestion strategy in adults hospitalized for acute heart failure (AHF) can improve patient-centered outcomes. The main questions it aims to answer are: * Does this strategy shorten the length of stay and reduce early hospital readmissions? * Does this strategy improve patients' symptoms and quality of life ? Researchers will compare LUS to physical examination (PE).

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether using lung ultrasound to guide diuretic (fluid-removal) therapy leads to better outcomes for patients hospitalized with acute heart failure, compared to standard clinical assessment. **You may be eligible if...** - You are 18 or older - You are being admitted to a cardiac or general medical ward for acute heart failure (fluid buildup) - Your blood levels of a heart stress marker (NT-proBNP) are above 1000 ng/L **You may NOT be eligible if...** - You have isolated right-sided heart failure - Your blood pressure is dangerously low - You have interstitial lung disease or lung cancer that mimics heart failure on ultrasound Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURELUS decongestive strategy

LUS results are documented in the electronic case report form (eCRF) and converted into a common score ranging from absence of congestion to severe congestion. This generic congestion score will be communicated to the treating physician by the research personnel, along with a proposal to step-up, maintain, or step-down the decongestive therapy.

PROCEDUREPE decongestive strategy

PE results are documented in the eCRF and converted into a common score ranging from absence of congestion to severe congestion. This generic congestion score will be communicated to the treating physician by the research personnel, along with a proposal to step-up, maintain, or step-down the decongestive therapy.