RecruitingPhase 2Phase 3NCT06466538

Investigate"Clinically" the Effectiveness of Boswellia Based Intracanal Medication Compared to Calcium Hydroxide Ca(OH)2 and Ledermix on the Levels of Bacteria and Inflammatory Cytokines in Root Canals and Periradicular Tissues of Teeth With Apical Periodontitis

Effectiveness of Boswellia as Intracanal Medication on Infectious/Inflammatory Contents in Teeth With Apical Periodontitis


Sponsor

Mansoura University

Enrollment

36 participants

Start Date

Jun 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this study is to investigate "clinically" the effectiveness of Boswellia based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.


Eligibility

Min Age: 20 YearsMax Age: 60 Years

Inclusion Criteria2

  • Single-rooted with pulp necrosis and apical periodontitis.
  • The age range from 20 to 60 years

Exclusion Criteria4

  • Receiving antibiotic treatment within the preceding 3 months.
  • Reporting systemic disease.
  • Teeth that could not be isolated with rubber dam.
  • Teeth with periodontal pockets deeper than 3 mm.

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Interventions

DRUGCalcium hydroxide

intracanal medicament

DRUGLeddermix

Leddermix

DRUGBoswellia

Boswellia


Locations(1)

May Abuzoor

Al Mansurah, Egypt

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NCT06466538


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