RecruitingPhase 3NCT06467097

Systemic Treatment Alone Versus Systemic Treatment Plus Radiotherapy in Oligometastatic Renal Cell Carcinoma

A Phase Ⅲ Randomized Study Systemic Treatment Alone Versus Systemic Treatment Plus Stereotactic Abative Body Radiotherapy for Patients With Oligometastatic Renal Cell Carcinoma: SABLOR Study


Sponsor

Samsung Medical Center

Enrollment

88 participants

Start Date

Apr 16, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate whether incorporating locoregional radiotherapy in the treatment of oligometastatic renal cell carcinoma, including inductive oligometastases, along with standard systemic therapy, contributes to improved progression-free survival rates for patients.


Eligibility

Min Age: 20 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two treatment strategies for kidney cancer that has spread to only a few sites (called oligometastatic disease): systemic drug treatment alone versus systemic drug treatment combined with targeted radiation to the metastatic sites. **You may be eligible if...** - You are between 20 and 80 years old - You have clear cell renal (kidney) cancer with 5 or fewer metastases in 3 or fewer organs - Your individual metastases are each no larger than 5 cm - Your primary kidney tumor has been or will be surgically removed - You are in good health (ECOG 0-1) **You may NOT be eligible if...** - You have more than 5 metastases or involvement of more than 3 organs - Your metastases are larger than 5 cm each Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONSBRT(Stereotatic Body Radiation Therapy)

Patients will receive treatment for one to two weeks, one to five times per region.


Locations(1)

Samsung Medical Center

Seoul, South Korea

View Full Details on ClinicalTrials.gov

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NCT06467097


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