RecruitingPhase 1Phase 2NCT06467318

Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax?

Sponsor

Ain Shams University

Enrollment

116 participants

Start Date

Sep 1, 2023

Study Type

INTERVENTIONAL

Conditions

Primary and Secondary Spontaneous Pneumothorax

Summary

Investigators aim to assess if NSAIDs affect the quality of pleurodesis resulting from mechanical pleurodesis (open surgery or VATS) regarding : Primary outcome: Recurrence of pneumothorax in 6 monthes. (assessed by X ray after 2 weeks and 6 months or symptoms requiring X ray at any timing) Secondary outcome: ▪ Adjusted Length of stay ( from day zero surgery day to discharge ). ▪ Time of removal of the chest Tube .(relatively longer with air leak presence). ▪ Need of opioids (N-SAID may decrease the need of opioids) .

Eligibility

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called NSAID, Paracetamol and a drug called Paracetamol for people with primary and secondary spontaneous pneumothorax. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGParacetamol

Participants post mechanical pleurodesis on pneumothorax will be divided into two groups: Group A: patients taking classic pain management with NSAID. Group B: patients taking classic pain management without NSAID.

DRUGNSAID, Paracetamol

Locations(1)

Faculty of medicine, Ain shams university

Cairo, Egypt

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NCT06467318