RecruitingNCT06467630

Measurement of the Performance and Safety of RTR+Membrane in Guided Tissue Regeneration (GTR) in Dental Surgical Procedures

Prospective, National, Multicentre and Observational Clinical Investigation of R.T.R.+ Membrane Used in Guided Tissue Regeneration (GTR) in Dental Surgical Procedures


Sponsor

Septodont

Enrollment

90 participants

Start Date

Feb 9, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to measure in real practice the performance and safety of RTR+Membrane, a synthetic dental membrane for guided tissue regeneration in periodontal or dental implant surgery. The main question it aims to answer is to measure the post-operative wound healing several months after surgery. Participants will be followed after their dental surgery via clinical examination and radiological and photos images.


Eligibility

Min Age: 18 YearsMax Age: 89 Years

Inclusion Criteria4

  • Male or female adult patient
  • Patient with one of the 3 following dental treatments to be done with the study device: post-extraction socket preservation, alveolar ridge augmentation, or Guided Tissue Regeneration (GTR) during immediate implant placement.
  • Patient affiliated or beneficiary of a social security system.
  • Patient has signed his/her informed consent form.

Exclusion Criteria9

  • Pregnancy or lactation
  • Active tissue infection at the implant site
  • Several dental treatments done simultaneously in non-contiguous dental zones
  • Heavy smoker (\>10 cigarettes / day)
  • Patient receiving long-term corticosteroid therapy, anti-rejection drugs, bisphosphonates, head \& neck radiotherapy or chemotherapy
  • Patient with chronic infections (such as osteomyelitis) at the surgical site
  • Patient with poorly controlled metabolic disorders (such as diabetes, osteomalacia, thyroid disorders)
  • Patient with an auto-immune disease
  • Patient under tutelage, vulnerable person, person without liberty, or unable to complete questionnaire independently

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Interventions

PROCEDUREPreserving alveolar bone volume after tooth extraction

* Visit 1: A periodontal or dental implant surgery is done aiming to preserve alveolar bone volume after extraction * Visit 2 (10 days ± 4 days) - Early post-surgery follow-up * V2bis (1 month +/- 1 week) - Early post-surgery follow-up * Visit 3 (5 months ± 1 month) - Late post-surgery follow-up

PROCEDUREAlveolar crest reconstruction

* Visit 1: A periodontal or dental implant surgery is done aiming to alveolar crest reconstruction * Visit 2 (10 days ± 4 days) - Early post-surgery follow-up * Visit 3 (5 months ± 1 month) - Late post-surgery follow-up

PROCEDURECovering bone defects during immediate implant placement.

* Visit 1: A periodontal or dental implant surgery is done aiming to cover bone defects during immediate implant placement. * Visit 2 (10 days ± 4 days) - Early post-surgery follow-up * Visit 3 (3 months ± 1 month) - Late post-surgery follow-up


Locations(9)

Hospital University of Nantes

Nantes, France

Private dental practice office of Dr. Alain Hoornaert

Nantes, France

Private dental practice office of Dr. Samer Saloum-Rouxel

Nantes, France

Private dental practice office of Dr. Xavier Struillou

Nantes, France

Private dental practice office of Dr. Edouard Lanoiselée

Nozay, France

Private dental practice office of Dr. Aurélien Fruchet

Olonne-sur-Mer, France

Private dental practice office of Dr. Hélène Le Hécho

Orée d'Anjou, France

Private dental practice office of Dr. Nicolas Strube

Orvault, France

Private dental practice office of Dr. Romain Besnier

Orvault, France

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NCT06467630


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