RecruitingNot ApplicableNCT06470516

The Hi-tACS on Cognitive Function in Patients With Schizophrenia

The Impact of High-frequency Transcranial Alternating Current Stimulation (Hi-tACS) on Cognitive Function in Patients With Schizophrenia


Sponsor

Sir Run Run Shaw Hospital

Enrollment

100 participants

Start Date

Apr 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study is a double-blind, randomized, controlled intervention study aimed at exploring whether high-frequency transcranial alternating current stimulation (Hi-tACS) can improve cognitive impairment in patients with schizophrenia.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing high-definition transcranial alternating current stimulation (a non-invasive brain stimulation technique using mild electrical current) to see if it can improve thinking and memory problems in people with schizophrenia. **You may be eligible if...** - You are 18 or older and have a diagnosis of schizophrenia according to DSM-5 criteria - You are right-handed - Your condition is currently stable and you have been on a steady dose of antipsychotic medication for at least 4 weeks - Your cognitive score on a standard test is 10 or higher **You may NOT be eligible if...** - Your psychotic symptoms are caused by another condition (bipolar disorder, drug use, anxiety disorder, etc.) - You have an unstable psychiatric condition or recent medication changes - You have a history of seizures or brain injury - You have metal implants in the head that would be unsafe with electrical stimulation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEhigh-frequency transcranial alternating current stimulation

The experimental group received real stimulation of high-frequency transcranial alternating current stimulation (Hi-tACS).The treatment duration is 30 days, with two sessions per day, each lasting 40 minutes.The experimental group received Hi-tACS with parameters set at 77.5Hz and 15mA.

DEVICEsham high-frequency transcranial alternating current stimulation

The the control group received sham stimulation of high-frequency transcranial alternating current stimulation (Hi-tACS).The treatment duration is 30 days, with two sessions per day, each lasting 40 minutes.The experimental group received Hi-tACS with parameters set at 0mA


Locations(2)

Sir Run Run Shaw Hospital

Hanzhou, Zhejiang, China

Quzhou Third Hospital

Quzhou, Zhejiang, China

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NCT06470516


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