RecruitingPhase 1Phase 2NCT06471946

VA Conditioning Regimen Allo-HSCT for Elderly Higher-risk MDS

Venetoclax Plus Azacytidine Conditioning Regimen Allo-HSCT for Elderly Patients With Higher-risk Myelodysplastic Syndromes


Sponsor

Navy General Hospital, Beijing

Enrollment

54 participants

Start Date

Oct 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this phase 1/2 trial is to test the safety and efficacy of Venetoclax Plus Azacytidine Conditioning Regimen Allo-HSCT in treating patients with higher-risk MDS.


Eligibility

Min Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Venetoclax Plus Azacytidine Conditioning Regimen Allo-HSCT for people with higher risk myelodysplastic syndromes. The study is currently recruiting participants at 1 location. People eligible for this study include aged 70 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGVenetoclax Plus Azacytidine Conditioning Regimen Allo-HSCT

Patients were treated by VA Conditioning Regimen Allo-HSCT: Venetoclax 100mg po qd d1, 200mg po qd d2, 400mg po qd d3-14; Azacytidine 75 mg/m2 subcutaneous injection qd d1-7, donor stem cells infused from d9


Locations(1)

Navy General Hospital

Beijing, Beijing Municipality, China

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NCT06471946


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