RecruitingNCT06472947

Non-invasive Evaluation of Graft Condition in Adult Patients With Kidney Transplant Using Ultrasound Localization Microscopy and Multispectral Optoacoustic Tomography


Sponsor

University of Erlangen-Nürnberg Medical School

Enrollment

10 participants

Start Date

Jun 18, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

In this study, the condition of the kidney transplant in adults is to be assessed non-invasively using Multispectral Optoacoustic Tomography and Ultrasound Localization Microscopy (ULM). ULM imaging can be performed in a 2-dimensional and a 3-dimensional way (2D and 3D ULM). Therefore, "ULM" in the following texts and measures will refer to 2D and 3D ULM. New, non-invasive markers that allow conclusions to be drawn about the condition of the transplant should reduce the need for invasive diagnostic procedures in the future.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • kidney transplant
  • indication for biopsy set in clinical routine
  • minimum 18 years of age
  • written consent

Exclusion Criteria5

  • allergy against contrast agents/ SonoVue
  • tatoos in examined areas
  • contraindication against SonoVue
  • pregnant women
  • breast feeding women

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Interventions

DEVICEULM and MSOT

transplanted kidney will be examined non-invasively with ULM and MSOT


Locations(1)

Department of Pediatrics and Adolescent Medicine

Erlangen, Bavaria, Germany

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NCT06472947


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