RecruitingPhase 2Phase 3NCT06474247

Postbiotic as Adjunct Treatment for Vaginal Candidiasis

Use of Postbiotic as Adjunct Treatment for Vaginal Candidiasis in Women


Sponsor

Min-Tze LIONG

Enrollment

118 participants

Start Date

Jun 2, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This project aims to study the efficacy of intravaginal administration of postbiotic at 1g/day as an adjunct treatment against vaginal candidiasis in women for 4-weeks compared to placebo.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 81 Years

Inclusion Criteria3

  • Women who are sexually active
  • Confirmed with candidiasis as confirmed via clinical observations which include creamy whitish vaginal discharge and vulva-vaginal itchiness
  • Willing to commit throughout the experiment

Exclusion Criteria11

  • Long term medication (6 months or more) for any illnesses
  • Pregnant
  • Menopaused
  • Uterus and/or cervix removed
  • Cervical intraepithelial neoplasia
  • Vaginal suppository treatments within 4-weeks prior to entering the study
  • Oral medication for vaginal illnesses or any vaginal therapy such as hormones and estrogen within 4-weeks prior to entering the study
  • Have used vaginal estrogen cream, ring or tablet within 4-weeks prior to entering the study
  • Have used vaginal moisturizers, lubricants or homeopathic preparations within 4-weeks prior to entering the study
  • Have used spermicide agent within 4-weeks prior to entering the study
  • Have pelvic or any gynecologic surgery 6-months prior to entering the study

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Interventions

DEVICEPostbiotic

Postbiotic at 1g/day as an adjunct treatment against vaginal candidiasis in women for 4-weeks

DEVICEPlacebo

Placebo at 1g/day as an adjunct treatment against vaginal candidiasis in women for 4-weeks


Locations(2)

Sumita Hospital

Lucknow, Aliganj, India

AIMST University

Bedong, Kedah, Malaysia

View Full Details on ClinicalTrials.gov

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NCT06474247