RecruitingNCT06477783

Study on the Clinical Efficacy of Teclistamab

Prospective Observational Study on the Clinical Efficacy of Teclistamab in Patients With Relapsed and Refractory Multiple Myeloma in Belgium


Sponsor

Universitaire Ziekenhuizen KU Leuven

Enrollment

100 participants

Start Date

Dec 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this study is to assess the clinical efficacy and safety of the anti-BCMA/CD3 bispecific antibody teclistamab (Tecvayli®) in a prospective, real-life setting in Belgium.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study collects real-world data on how well teclistamab — a recently approved immunotherapy for multiple myeloma — works in everyday clinical practice outside of a controlled trial setting. **You may be eligible if...** - You are 18 or older with relapsed and refractory multiple myeloma (cancer of plasma cells in the bone marrow that has come back or stopped responding to treatment) - You have already received at least three prior treatments - Your cancer has stopped responding to at least one proteasome inhibitor, one immunomodulatory drug, and an anti-CD38 antibody - Your doctor has decided to start you on teclistamab as part of routine care **You may NOT be eligible if...** - You have previously participated in a teclistamab clinical trial - You started teclistamab more than 14 days before the screening visit Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGTeclistamab

Intervention is part of standard clinical care, as Tecvayli/Teclistamab is reimbursed for this group of patients.


Locations(17)

Imelda

Bonheiden, Antwerpen, Belgium

Universitair Ziekenhuis Antwerpen (UZA)

Edegem, Antwerpen, Belgium

Grand Hôpital de Charleroi

Charleroi, Henegouwen, Belgium

EpiCURA

Hornu, Henegouwen, Belgium

CHU Ambroise Paré

Mons, Henegouwen, Belgium

Jessa Ziekenhuis

Hasselt, Limburg, Belgium

CHR Citadelle

Liège, Liège, Belgium

CHU Liège

Liège, Liège, Belgium

CHU UCL Namur

Yvoir, Namur, Belgium

Algemeen Ziekenhuis Maria Middelares (AZMM)

Ghent, Oost-Vlaanderen, Belgium

Universitair Ziekenhuis Gent (UZ Gent)

Ghent, Oost-Vlaanderen, Belgium

Vitaz

Sint-Niklaas, Oost-Vlaanderen, Belgium

Institut Jules Bordet

Brussels, Vlaams-Brabant, Belgium

UCL Saint Luc

Brussels, Vlaams-Brabant, Belgium

AZ Groeninge

Kortrijk, West-Vlaanderen, Belgium

AZ Delta

Roeselare, West-Vlaanderen, Belgium

UZ Leuven Gasthuisberg

Leuven, Belgium

View Full Details on ClinicalTrials.gov

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NCT06477783


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