Antibiotic Exposure During Pregnancy Affects Infant Gut Microbiota
Peking University People's Hospital
450 participants
Jun 25, 2023
OBSERVATIONAL
Conditions
Summary
Based on a prospective birth cohort, the investigators will collect biological samples from participants including pregnant women and newborns, to measure the gut microbial diversity and metabolites of newborns. These results systematically evaluate the effects of antibiotic exposure on the structure and function of gut microbiota. The project can reveal the effects of antibiotic exposure on the growth and development of gut microbiota in early life.
Eligibility
Inclusion Criteria8
- Pregnant woman
- aged 20-40 years old
- natural conception
- single pregnancy
- gestational age ≥36 weeks
- Newborn
- normal Apgar score
- no serious congenital diseases
Exclusion Criteria1
- \-
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Interventions
AT: Mother-infant cohort with antibiotic treatment group CS: Mother-infant cohort (Prophylactic antibiotics therapy) ND: Mother-infant cohort (Natural delivery)
Locations(1)
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NCT06479941