Eccentric Cycling Exercise During Pulmonary Rehabilitation Pulmonary Vascular Disease

This study is investigating whether eccentric cycling — a type of exercise where muscles work while lengthening rather than shortening, allowing high-intensity training at lower energy cost — can improve exercise capacity and lung blood vessel function in patients with pulmonary vascular disease (PVD), including pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Adults aged 18 to 85 diagnosed with PVD according to recent guidelines who are on stable medication for at least one month and do not have low resting oxygen levels may be eligible. Participation involves attending a structured rehabilitation program using an eccentric cycling bike and being assessed for exercise capacity and heart-lung function before and after. This summary was prepared to help patients understand the study in plain language.