RecruitingNCT06480994

Exclusion of Venous Thrombo-Embolism With a New Clinical Decision Support

Exclusion of Venous Thrombo-Embolism With a New Clinical Decision Support With Fresh Plasma, on Any Patient With VTE Suspicion


Sponsor

Diagnostica Stago R&D

Enrollment

1,836 participants

Start Date

Jun 21, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this non interventional study is to demonstrate the diagnostic performances on fresh plasmas in comparison with the performances on frozen plasmas in any patients with VTE suspicion, whatever the pre-test probability. The main question it aims to answer is : Are the performances equivalent on fresh plasmas in comparison with frozen plasmas or is it necessary to determine a new algorithm of the Clinical Decision Support with a new cut-off? Participants will be diagnosed and treated in accordance with routine standard of care.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • PE and/or DVT suspicion
  • No opposition after informing the patient for his participation in research and processing of their data for this purpose,
  • Benefiting from the social security system

Exclusion Criteria3

  • Preventive or curative anticoagulant treatment, or fibrinolytic treatment,
  • Legal protection (e.g. guardianship or curatorship),
  • Pregnant or breastfeeding women.

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Interventions

DIAGNOSTIC_TESTRoutine Assays on fresh plasma

Routine coagulation tests using STA-R Max analyzer : Prothrombin Time (PT) activated Partial Thromboplastin Time (aPTT Thrombin Time (TT) Fibrinogen Anti-Xa activity

DIAGNOSTIC_TESTNew Clinical Decision Support on fresh plasma

D-Dimer and fibrin formation assays on STA-R Max analyzer. Calculation of the exclusion score using an algorithm (manual or based on Machine Learning) compared to a Clinical Decision Support cut-off.

DIAGNOSTIC_TESTNew Clinical Decision Support on frozen plasma

D-Dimer and fibrin formation assays on STA-R Max analyzer. Calculation of the exclusion score using an algorithm (manual or based on Machine Learning) compared to a Clinical Decision Support cut-off.


Locations(4)

Centre Hospitalier de Niort

Niort, Sartres, France

Centre Hospitalier le Mans

Le Mans, Sartre, France

CHU Dijon Bourgogne

Dijon, France

University Hospital Grenoble

Grenoble, France

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NCT06480994


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