A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

This study is testing lifileucel — a treatment made from tumor-infiltrating lymphocytes (TIL), which are immune cells extracted from your own tumor, multiplied in a lab, and reinfused to fight cancer — in adults with advanced endometrial (uterine lining) cancer that has come back or stopped responding to treatment. **You may be eligible if...** - You are 18 or older with advanced endometrial carcinoma (all types except uterine sarcoma) - You have received between 1 and 4 prior lines of treatment, including both platinum-based chemotherapy and an immunotherapy (anti-PD-1/PD-L1) drug - You have measurable disease that can be tracked on scans - Your general health is adequate (ECOG 0–2) - You have tumor tissue available for cell extraction **You may NOT be eligible if...** - You have uterine sarcoma (a different type of uterine cancer) - You have active brain metastases or severe autoimmune disease - You are pregnant or breastfeeding - You have had more than 2 lines of chemotherapy Talk to your doctor to see if this trial is right for you.