RecruitingNCT06481826

Glofitamab in Chinese Patients With R/R DLBCL

A Study to Evaluate Glofitamab as Single Agent in Chinese Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma


Sponsor

Peking Union Medical College Hospital

Enrollment

20 participants

Start Date

Jan 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This study will evaluate the safety and efficacy of glofitamab as a single agent in Chinese patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who have failed two or more lines of systemic therapy.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is testing glofitamab — a type of immune therapy called a bispecific antibody that helps your immune system find and destroy cancer cells — in Chinese patients with diffuse large B-cell lymphoma (DLBCL) that has come back or stopped responding to treatment. **You may be eligible if...** - You have been diagnosed with DLBCL confirmed by biopsy - Your lymphoma has relapsed (come back) or did not respond to at least two prior treatment regimens - You have measurable disease visible on scans **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have a known active infection or a reactivated latent infection - You have an active autoimmune disease or immune deficiency - You have severe organ problems (poor heart function, poor lung function, low kidney function, or high bilirubin) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGGlofitamab

Glofitamab given in standard dosage


Locations(1)

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

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NCT06481826


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