Shortened High-dose Palliative Radiotherapy for Lung Cancer

This study is testing a shortened version of high-dose palliative radiation therapy for people with advanced (stage IIIB–IV) non-small cell lung cancer (NSCLC). The goal is to deliver effective radiation in fewer sessions, making treatment more convenient while still controlling symptoms and local disease. **You may be eligible if...** - You are 18 or older - You have been diagnosed with locally advanced (stage IIIB/IIIC) or metastatic (stage IV) NSCLC - You are either treatment-naive (no prior treatment) or had limited progression after one line of systemic therapy (chemo, immunotherapy, or targeted therapy) - Your doctor has recommended high-dose palliative radiation therapy for you **You may NOT be eligible if...** - You have already received two or more lines of systemic therapy for NSCLC - You have more than one type of cancer - You have a contraindication to thoracic radiation - Your first-line treatment cannot be started within a few weeks of radiation Talk to your doctor to see if this trial is right for you.