RecruitingNot ApplicableNCT06492967

LatAm-FINGERS Initiative for Cognitive Change

Latin American Lifestyle Intervention Initiative to Reduce the Risk and Prevent Cognitive Impairment.


Sponsor

Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia

Enrollment

1,200 participants

Start Date

Sep 1, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Currently, 40% of global dementia cases can be prevented through lifestyle changes, with Latin America having a 56% potential reduction due to its high-risk factors. At the moment, there are no medications that halt the clinical expression of dementia. LatAm-FINGERS, a multicenter study across 12 Latin American countries, aims to study the feasibility of an intervention modifying lifestyle in individuals aged 60 to 77 at risk of dementia. Success could influence public policy on clinical care for older adults.


Eligibility

Min Age: 60 YearsMax Age: 77 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing a comprehensive lifestyle program — combining diet, exercise, brain training, and social activities — to protect memory and thinking skills in older adults across Latin America who are at increased risk of developing dementia. **You may be eligible if...** - You are between 60 and 77 years old - You have multiple risk factors for dementia (scored above 6 on a standard risk tool) - Your memory or thinking shows a mild decline (just below average on standard tests) **You may NOT be eligible if...** - You already have a diagnosis of dementia - Your score on the standard mental status exam is below 20 (indicating significant impairment) - You have a medical condition that would make it unsafe to participate - You have severe joint or mobility problems that would prevent you from doing the physical activity part of the program Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALSystematic Lifestyle Intervention

Lifestyle intervention that involves providing participants with education, support, and tangible tools to assist them in developing and carrying out healthier lifestyle practices.

BEHAVIORALFlexible Lifestyle Intervention

Lifestyle intervention that involves a structured program of diet, physical and cognitive exercise, and management of cardiometabolic risks.


Locations(13)

Fleni

Ciudad Autonoma de Buenos Aire, Argentina

Centro Neurológico Mente Activa

La Paz, Bolivia

Universidade Federal de Minas Gerais

Belo Horizonte, Minas Gerais, Brazil

University of Sao Paulo School of Medicine

São Paulo, Brazil

Hospital Clínico Universidad de Chile

Santiago, Chile

Antioquia University

Antioquia, Colombia

Hospital Clínica Bíblica

San José, Costa Rica

Universidad Nacional Pedro Henriquez Urena (UNPHU)

Santo Domingo, Dominican Republic

Neuromedicenter - Cognitive Disorders Unit

Quito, Ecuador

Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez

Mexico City, Mexico

Instituto Peruano de Neurociencas

Lima, Peru

Universidad de Puerto Rico

San Juan, Puerto Rico

Clínica de la Memoria - Hospital Británico

Montevideo, Uruguay

View Full Details on ClinicalTrials.gov

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NCT06492967


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