RecruitingPhase 3NCT06494878

The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity

The PARTUM (Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity) Trial

Sponsor

University of Calgary

Enrollment

8,805 participants

Start Date

Jun 4, 2026

Study Type

INTERVENTIONAL

Conditions

Venous Thromboembolism Aspirin Postpartum Period Low Molecular Weight Heparin

Summary

The goal of the PARTUM trial is to determine if taking low-dose aspirin daily for 6 weeks after delivery is similar (non-inferior) to usual care low-molecular-weight heparin injections to prevent venous thromboembolism (VTE: blood clots in the legs or lungs) for postpartum individuals with VTE risk factors.

Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Aspirin and a drug called Low-molecular-weight heparin for people with aspirin, low molecular weight heparin, and other related conditions. The study is currently recruiting participants at 12 locations. People eligible for this study include women aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGAspirin

75-100 mg taken once daily by mouth.

DRUGLow-molecular-weight heparin

Low-molecular-weight heparin injections daily as prescribed by the treating physician.

Locations(12)

Association Hospitalière De Bruxelles Et De Schaerbeek - Centre Hospitalier Universitaire Brugmann

Brussels, Belgium

Foothills Medical Centre

Calgary, Alberta, Canada

The Ottawa Hospital - General Campus

Ottawa, Ontario, Canada

Hvidovre Hospital

Hvidovre, Capital Region, Denmark

CHU de Nancy

Nancy, France

APHP - Hôpital Port Royal

Paris, France

CHU de Saint-Etienne

Saint-Etienne, France

CHU de Toulouse

Toulouse, France

Rotunda Hospital, RCSI Department of Obstetrics and Gynaecology

Dublin, Ireland

UCD Centre for Human Reproduction, The Coombe Hospital

Dublin, Ireland

Amsterdam UMC

Amsterdam, Netherlands

Medical University of Warsaw

Warsaw, Poland

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06494878

Related Trials

DOAC in Chinese Patients With Atrial Fibrillation

NCT053780351 location

Aspiration Thrombectomy Using the Symphony or Prodigy System

NCT073504998 locations

DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

NCT0570191764 locations

Colchicine to Quench the Inflammatory Response After Deep Vein Thrombosis (The Conquer-DVT Pilot Trial)

NCT064406944 locations

Reducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous Thromboembolism

NCT063938687 locations